Question: Generating simulated gene expression data sample based on DESeq2 result
gravatar for bharata1803
4.3 years ago by
bharata1803450 wrote:


I have a result of DESeq2 analysis of RNA-seq sample. In that result, it is mentioned about the baseMean and I think that baseMean is the mean of negative binomial distribution which is the distribution used by DESeq2. My question is, how to generate a sample following the distribution like used in DEseq2 with given mean from DESeq2? I don't know about the variation of the distribution though because it seems there are no variation variable there. Thank you.

rna-seq R • 1.4k views
ADD COMMENTlink modified 4.3 years ago by Biostar ♦♦ 20 • written 4.3 years ago by bharata1803450

So your goal is: given the results of a DESeq2 analysis, generate simulated sequence data which could have generated the given DESeq2 result?

ADD REPLYlink written 4.3 years ago by mbio.kyle360
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 706 users visited in the last hour