I read multiple papers on cancer multi-platform genomics data that used Cluster of cluster analysis to see consensus in the different platforms.
I want to do the same but I am confused with the steps- 1. So I do clustering on each dataset and get cluster information (like cluster assignment) so this can be number 1- k 2. The paper says-
"Briefly, subtype calls from each of the following 4 platforms: mRNA, miRNA, methylation, and copy number were used to identify relationships between the different data type’s classifications. Subtypes defined from each platform were coded into a series of indicator variables, resulting in a matrix of 1s and 0s. Hierarchical clustering of this matrix was performed using the ConsensusClusterPlus R-package"
Iam not sure how this matrix was just 0 and 1s?
Anyone familiar who can help?