Question: calculating FDR threshold for FST and PBS statistics
gravatar for ald4786
3.1 years ago by
ald47860 wrote:

I have fixation index statistics (FST) for approximately 4 million loci, genome-wide. I would like to calculate a 5% FDR threshold in order to select the top loci in terms of highest FST statistics. Population genetics papers often take the top x% FDR for FST and PBS stats, but do not state in methods how they calculate the FDR threshold.

I have tried calculating P-values, then calculating q values using fdrtool in R, but these FDR thresholds seem to be falling very low (not stringent at all). Can someone explain what it means to take a top x% FDR?

ADD COMMENTlink written 3.1 years ago by ald47860
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 791 users visited in the last hour