chromosome alignment tool
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8.1 years ago
cldick • 0

is there a tool that can align entire genomes, and produce an output that shows where translocations and inversions have occurred in the evolutionary divergence of two species? i'm hoping that the output will include a graphic representation of the chromosomes aligned between two species. this could be used to compare the chromosomes of a human and a chimpanzee, or a cat and a dog, or a rabbit and a bear, or whatever. i'm expecting that any two mammals should have enough similarity that they should be meaningfully comparable. then if, for example, a single rabbit chromosome aligns highly with a single feline chromosome, they could be experimentally exchanged to see if the resulting animal is viable.

genome alignment blast next-gen • 1.8k views
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8.1 years ago
mastal511 ★ 2.1k

Have a look at the Wikipedia entries for 'Synteny' and for 'Comparative Genomics'.

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