Frequency of codon mutation in cancer

Question

[umn_bist]

I was curious if this metric is available at IARC or elsewhere. I would like to know how frequently a P47S (SNV) occurs across different cancer types. Or just mutation frequency at codon 47 across different cancer types.

This is a validated polymorphic site but I could not obtain this piece of data from IARC P53 database.

Answer 1

[elham_shams21]

With what software can be used to assess the P53 mutations

Answer 2

[chen]

Maybe you can find this information from COSMIC database

Answer 3

[igor]

COSMIC TP53 P47S: http://cancer.sanger.ac.uk/cosmic/mutation/overview?id=5347102

Found in only two COSMIC samples and never confirmed as somatic.