Library preparation for Ion Torrent Platforms

Question

[Wet&DryImmunology]

I was preparing Sequence library for Ion Torrent Platforms. and I have one strange result when performing the library QC check.

I have two biological samples. When using 4200TapeStation to check the quality of libraries:

one sample displayed one continuous band center at 300bps, spanning from 200bps to roughly 400bps.

the other sample displayed sort of strange band pattern (several discrete sharp bands, 91, 140, 178,210, 252,290,327) Dose anyone have any idea about what might go wrong?

I understood biostar is a community about dry analysis, if there are better place to ask the question, please also kindly let me know. Thanks!

[venu]

You can ask these type of questions here and there is Ion Community which helps in resolving issues specific to Ion Torrent technologies.