Question: Is there more genetic variation at the edges of haplotypes?
gravatar for Floris Brenk
13 months ago by
Floris Brenk790
Floris Brenk790 wrote:

Hi all, During a presentation few weeks ago someone said that there is more genetic variation at the edges of haplotypes. Is this really the case? I have been thinking about but can't really find an explanation for this why this would be the case and why the variation would be at the edge of haplotypes and not in the middle, or is this the term of recombination hotspots? Does anyone have an explanation or reference for this? Reason why I'm interested in this is that there was a recent paper suggesting that there might be two separate founder (risk for disease) haplotypes based on that there is variation at the edges of this haplotypes. While I just always assumed this was because of evolutionary variation...

haplotype genome • 319 views
ADD COMMENTlink written 13 months ago by Floris Brenk790
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