Hi all, During a presentation few weeks ago someone said that there is more genetic variation at the edges of haplotypes. Is this really the case? I have been thinking about but can't really find an explanation for this why this would be the case and why the variation would be at the edge of haplotypes and not in the middle, or is this the term of recombination hotspots? Does anyone have an explanation or reference for this? Reason why I'm interested in this is that there was a recent paper suggesting that there might be two separate founder (risk for disease) haplotypes based on that there is variation at the edges of this haplotypes. While I just always assumed this was because of evolutionary variation...
Question: Is there more genetic variation at the edges of haplotypes?
18 months ago by
Floris Brenk • 800
Floris Brenk • 800 wrote:
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