generate consensus sequence from unphased heterozygous calls
0
0
Entering edit mode
5.4 years ago
atul_shah1 • 0

I'd like to generate a single consensus by substituting a set of unphased snp and indel variant calls, each with specified zygosity, into a reference sequence. A heterozygous snp can be represented by an IUPAC ambiguity code from {R,Y,S,W,K,M}. Is there a standard designation of a het indel? e.g. an ambiguity code to indicate either a base or a "gap", i.e. (A,-), (C,-), etc. at a particular position? Some other community standard for designating heterozygosity? Thanks for your help!

Heterozygous Indel consensus sequence unphased • 1.4k views
ADD COMMENT

Login before adding your answer.

Traffic: 2287 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6