How to get reference data for impute2 when imputing gwasdata
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7.5 years ago

Hi,everyone! I'm writting to ask you a question about a problem I met when I use Impute2 to impute my gwas data.It is one of the reference data ,"1000GP_Phase3_chr3.hap.gz "downloaded from the website https://mathgen.stats.ox.ac.uk/impute/1000GP_Phase3.html ,that is unable to gunzip. I have tried the 3rd time to download the whole file(10GB) and it comes the same.And I have wrote to the author but without reply.So I am here to plead for your help . How can I get the reference data in another way.

Thanks for your attention .Wish you have a good day.

SNP • 1.6k views
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Which platform are you doing this on? Should be possible on unix if there's enough disk space and memory. If you are able to download the file without any issues, split the file (split, head, etc), then concatenate the smaller files using cat or gzip -- I am assuming memory is the limiting factor.

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