I have 500+ MAF files of exome sequencing. I want to get the allele frequency for all population in Exac.
I have used awk script to match my variants in MAF files with the VCFs from EXac database. However, Exac only provides the allele count and allele number (AC ; AN) for population specific and I need to calculate the frequency.
Is there a tool or script available to calculate the population specific allele frequency from Exac database ?