Entering edit mode
7.0 years ago
NgForin
•
0
Hi all,
I'm going to calculate co-occurrence statistics among several TF peaks. Homer document says mergePeaks uses hypergeometric distribution to calculate p value for overlap but the program only takes genome size as background.
- How they establish the hypergeometric model? Does mergePeaks ignore continuity of peaks and only use base as unit?
- If I want to get co-occurrence statistics in TSS, intergenic, TTS and introns respectively, what background should I provide? Is there any existing tool for this task?
Thanks!