I am new to process somatic mutation by ICGC data. In
simple_somatic_mutation.aggregated.vcf.gz(https://dcc.icgc.org/releases/current/Summary), I got
vcf format file. Every
Mutation ID in the data annotated how many
donor affected. Is this the mutation number? When I wanted more detail data, only
.tsv file provided. I am also confused about there are a number of same
Mutation ID. I mean, in a sample, why there are more than one record at same chromosome loci?
For example,https://dcc.icgc.org/donors/DO51576, this donor has a mutation ID MU28652212. It just affected one donor Across all Projects, while in
.tsv file of project LUSC-CN, there are 5 rows of MU28652212. When I compute the mutation counts, should I treat it as 1 mutation or 5 mutation?