Question: How should I compare multiple TF methylation percentages?
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gravatar for morovatunc
2.3 years ago by
morovatunc400
Turkey
morovatunc400 wrote:

Hi,

I would like to compare methylation percentage of multiple transcription factors. I have seen many differential methylation region analysis based on multiple samples but has any of you done this kind of analysis based on single sample and different subset of regions ?

My aim is to score every region of a bed file regarding its methylation percentage. So that I can get cumulative scores of that TF and make comparison.

  • For any given peak of a bed file how should I score methylation ?
  • Because methylation data is bimodal a simple box plot is looking very bad. Do you have a suggestion to show differences among TF binding regions methylation profile ?

I am very frasturated so any guidenence is very valuable,

Best,

Tunc.

tf methylation encode • 664 views
ADD COMMENTlink modified 2.3 years ago • written 2.3 years ago by morovatunc400
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