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6.9 years ago
nerfherder
•
0
I'm trying to assign breast cancer intrinsic subtypes to a cohort of tumor samples using an expression dataset (microarray). I've clustered the samples into subtypes using the PAM50 centroid-based predictor, but I'm interested in assigning the claudin-low subtype as well (not included in PAM50). I have the list of ~800 genes whose expression can predict this subtype, yet I'm not sure how to create the centroid-based predictor using this gene list.
Any advice or references would be much appreciated, thanks!