finding NCBI protein ID and associated COG ID
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7.4 years ago
bitpir ▴ 250

Hi there, I am new to the metagenomic field. I recently did a blastx of my contigs using the nr database. With the results, I plan to categorize the protein hits with COG_ID and COG functions. I am using the cog2003-2014.csv database that's available from the NCBI website, by looking up the protein id's (from the blastx results) and the associated COG ID. However, I realize that almost all of the protein id's in my blast results are not found in the cog2003-2014.csv database. Am I doing something wrong here? I am aware that the cog database is much smaller than the nr database, but is there another way to find the COG IDs for my proteins? I have tried to use Uniprot's retrieve/ID mapping website (http://www.uniprot.org/uploadlists/), however, it still doesn't give me the COG ID but rather the GO numbers. Is it possible then to use GO numbers to get to COG IDs? Thanks a lot!

blastx nr database COG • 2.3k views
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