**260**wrote:

Can someone please explain in detail the meaning of the following section of the paper
**2.2 Finding a candidate QTL per phenotype**
For simplicity, we will focus on a single molecular phenotype P
quantified in a set of N samples. Let G be the set of genotype dosages
at L variant sites located within a cis-window of 6 W Mb of
the genomic location of P. To discover the best candidate QTL for
P, FastQTL measures Pearson product-moment correlation coefficients
between P and all L variants in G, stores the most strongly
correlated variant q [ G as candidate QTL, and assesses its significance
by calculating a nominal P-value pn with standard significance
tests for Pearson correlation.
How can this be affected by a test where only one SNP and its LD proxies (r=0.8) is tested.
Thanks!

Please see: C: FastQTL - GNU Scientific Library (GSL) Domain Error

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