Question: ChIP-seq: Why MACS doesn't apply tag shifting to the control sample?
0
gravatar for salamandra
14 days ago by
salamandra70
salamandra70 wrote:

If I understand right, MACS shifts chip-seq tags of a fragment into 3┬┤end because the tags are just small sequences in the extremes of the fragment. But why does it only apply to the ChIP sample and not to the control samples (input DNA)? Or paired-end sequencing isn't done in control samples?

Ref: https://genomebiology.biomedcentral.com/articles/10.1186/gb-2008-9-9-r137

chip-seq • 117 views
ADD COMMENTlink written 14 days ago by salamandra70
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 945 users visited in the last hour