Can't I use STAR aligner in my laptop?

Question

[John]

Dear one, Can't I use STAR in my laptop which has 4GB RAM? I want to align mouse RNA-Seq data! It is written that STAR requires 30GB of RAM for human genome!

Thanks in advance!

Answer 1

[WouterDeCoster]

If you have only 4Gb, and you need 30Gb (which is the case), then no, you cannot run STAR on your laptop.

Perhaps you could have a look at more light-weight pseudoalignments using Salmon (depending on your downstream project of course!)