Question: tool to link transcription factors (DEGs) with target genes (DEGs)?
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gravatar for Muha0216
2.6 years ago by
Muha02160
Muha02160 wrote:

Is there an online tool where i can input in all my DEGs and see if there is possible link between transcription factors which were differentially expressed and its target genes which were also differentially expressed?

rna-seq • 1.3k views
ADD COMMENTlink modified 2.6 years ago by geek_y11k • written 2.6 years ago by Muha02160
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gravatar for geek_y
2.6 years ago by
geek_y11k
Barcelona
geek_y11k wrote:

You can look at cytoscape apps like iRegulone

I also came across TRRUST recently, which is a database of TF targets.

Keep in mind that TF regulation is very cell type specific and context dependent. The databases are built from data from various cell-types and different cellular context. So check information relevant to the organism / cell type you are working with.

ADD COMMENTlink modified 2.6 years ago • written 2.6 years ago by geek_y11k
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