Common Gene Expression Pattern From Matrix

Question

[nikitavlassenko]

I am using Seurat for my single cell RNA-seq dataset and I subset it to get a dataset of 80 cells vs 20 000 genes. Now I need to find genes that are expressed similarly across all of the 80 cells, similar patterns of expression. Can I do it with Seurat? What other software could I use for that and how?

Answer 1

[nikitavlassenko]

Ultimately I decided to subdivide the dataset into certain groups, and use FindMarkers function to do DE:

https://satijalab.org/seurat/de_vignette.html