I have gene expression data for 10 control and 10 treatment samples. For a particular gene I need to find the change between control and treatment and following are the steps that I think to do:
- Log2 transform
- Z-score calculation for control and treated together
- Standard deviation of z-scores for controls - Standard deviation of z-scores for treatment -> to find the change
Please let me know if this way is correct? If not, let me know the right way!