Question: Identifying driver mutations in mice cancer data
gravatar for banerjeeshayantan
2.3 years ago by
banerjeeshayantan190 wrote:

I have 10 normal-tumor samples containing mice PDAC data. I have already called variants and annotated them. Now I wanted to use conventional driver mutation tools to identify recurrently mutated variants in each of the samples. I was planning to use MutSigCV, but they are mostly used for the human genome and in their webpage, it's mentioned that future versions will include mice data as well. What should be an ideal approach here? Can you suggest some tools that will scale with mice cancer data as well?

sequencing snp assembly genome • 447 views
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