How to convert Merlin phased result files to vcf
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5.7 years ago
moxu ▴ 510

I used Merlin to do family trio phasing. Merlin generated a .chr file and a .flow file for each chromosome. I need to convert these files to .vcf files, or at least to a format that is more modern and popular.

Any suggestions/recommendations would be highly appreciated.

genome snp assembly software error • 1.3k views
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Entering edit mode
5.7 years ago
moxu ▴ 510

The answer is that mega2 cannot take Merlin's .chr/.flow as input and cannot convert them to .vcf. The suggestion I got from the mega2 professor is to use shapeit, which can do trio phasing and can convert to vcf.

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