Question: How to convert Merlin phased result files to vcf
0
gravatar for moxu
12 months ago by
moxu440
moxu440 wrote:

I used Merlin to do family trio phasing. Merlin generated a .chr file and a .flow file for each chromosome. I need to convert these files to .vcf files, or at least to a format that is more modern and popular.

Any suggestions/recommendations would be highly appreciated.

ADD COMMENTlink modified 12 months ago • written 12 months ago by moxu440
2
gravatar for moxu
12 months ago by
moxu440
moxu440 wrote:

The answer is that mega2 cannot take Merlin's .chr/.flow as input and cannot convert them to .vcf. The suggestion I got from the mega2 professor is to use shapeit, which can do trio phasing and can convert to vcf.

ADD COMMENTlink written 12 months ago by moxu440
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1615 users visited in the last hour