Question: How to convert Merlin phased result files to vcf
0
gravatar for moushengxu
8 days ago by
moushengxu310
moushengxu310 wrote:

I used Merlin to do family trio phasing. Merlin generated a .chr file and a .flow file for each chromosome. I need to convert these files to .vcf files, or at least to a format that is more modern and popular.

Any suggestions/recommendations would be highly appreciated.

ADD COMMENTlink modified 6 days ago • written 8 days ago by moushengxu310
2
gravatar for moushengxu
6 days ago by
moushengxu310
moushengxu310 wrote:

The answer is that mega2 cannot take Merlin's .chr/.flow as input and cannot convert them to .vcf. The suggestion I got from the mega2 professor is to use shapeit, which can do trio phasing and can convert to vcf.

ADD COMMENTlink written 6 days ago by moushengxu310
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