Question: de novo vs somatic caller Varscan
gravatar for ccscience76
14 months ago by
ccscience760 wrote:


Im trying to figure out to use different tools to study de novo variants from whole exome sequence.

If I merge the parental bam files(marking duplicates later and so on) and I use somatic variant caller from Varscan against the child, the results shouldn't be a bit similar if I use directly de novo(trio) caller tool from Var Scan?

Maybe this sounds a bit weird...but I would appreciate if someone can explain to me.


de novo exome • 349 views
ADD COMMENTlink modified 14 months ago • written 14 months ago by ccscience760
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 2537 users visited in the last hour