Question: de novo vs somatic caller Varscan
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gravatar for ccscience76
14 months ago by
ccscience760 wrote:

Hello

Im trying to figure out to use different tools to study de novo variants from whole exome sequence.

If I merge the parental bam files(marking duplicates later and so on) and I use somatic variant caller from Varscan against the child, the results shouldn't be a bit similar if I use directly de novo(trio) caller tool from Var Scan?

Maybe this sounds a bit weird...but I would appreciate if someone can explain to me.

Thanks

de novo exome • 349 views
ADD COMMENTlink modified 14 months ago • written 14 months ago by ccscience760
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