Intra-tumor Heterogeneity / Mutation Cellular Fraction in TCGA Data
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5.3 years ago
Noushin N ▴ 600

Hello,

I was wondering if anyone is aware of an online resource where information on mutation cancer cell fraction estimates for TCGA samples can be retrieved.

I am aware of two excellent studies which have performed the exact analysis to derive the above. But I cannot locate the corresponding values in the available supplementary data.

[1] Andor N, Graham TA, Jansen M, Xia LC, Aktipis CA, Petritsch C, Ji HP, Maley CC. Pan-cancer analysis of the extent and consequences of intratumor heterogeneity. Nature Medicine. 2016;22:105–113. doi: 10.1038/nm.3984.

[2] Morris LG, Riaz N, Desrichard A, Senbabaoglu Y, Hakimi AA, Makarov V, et al. Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival. Oncotarget. 2016;7:10051–10063. doi: 10.18632/oncotarget.7067

Thank you,

Noushin

TCGA Heterogeneity • 772 views
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