Differential Expression of lncRNAs in Brain --- Can a database aid my search?
1
0
Entering edit mode
5.3 years ago

I am searching for lncRNA expression differences within specific brain tissues (astrocytes vs neurons vs etc...) for humans. I have browsed numerous lncRNA databases (linked from https://en.wikipedia.org/wiki/List_of_long_non-coding_RNA_databases) and explored the ensembl regulatory build. That being said, I can''t find any comprehensive source that highlights that information.

Perhaps the only solution is to use publicly available RNA-seq data and perform the differential expression myself. But as I've never done that... and suspect others had this same question... I thought it would be prudent to post here.

Thus, I am hoping someone could either point me in the right direction or highlight what I should/shouldn't be doing. Perhaps there is a reason this information isn't readily available.

Thank you

lncRNA differential expression database • 1.1k views
ADD COMMENT
1
Entering edit mode
5.3 years ago
piyushjo ▴ 700

Hi JTA,

Nice to see another person looking for lncRNA in brain. I can share some resources I am aware of. http://www.brainspan.org/

http://www.cdtdb.neuroinf.jp/CDT/Top.jsp

Read these papers

http://www.jneurosci.org/content/38/10/2399

https://genome.cshlp.org/content/28/8/1097.full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657279/

The resources are very limited and you would have to do your own analysis and even for that you might not find a lot of raw data for human.

Hope it helps!

ADD COMMENT

Login before adding your answer.

Traffic: 2325 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6