Question: VCF INFO AC field for failed snps
gravatar for steven.davis
8 months ago by
steven.davis10 wrote:

What is the standard VCF INFO field, if any, to count the occurrences of variant genotypes having passed all filters?

Does AC count every occurrence of the alternate genotype, or only those occurrences where the call passes all filters?

Consider the haploid VCF snippet below. At position 300, the sample3 variant call does not pass all the filters. In this case, should AC be set to 1 or 2?

I need a field that counts only the variants passing all the filters. Should I invent something, use AC, or use some other standard field?

100 A    C,G  AC=1,1  GT:FT  0:PASS  1:PASS  2:PASS
200 A    C    AC=2    GT:FT  0:PASS  1:PASS  1:PASS
300 A    C    AC=1    GT:FT  0:PASS  1:PASS  1:FAIL
vcf • 397 views
ADD COMMENTlink modified 8 months ago • written 8 months ago by steven.davis10

Hello steven.davis ,

what you are showing is not valid vcf file. So the question is, do you have a valid vcf file (than show us) or does your file looks like you are showing here?

fin swimmer

ADD REPLYlink modified 8 months ago • written 8 months ago by finswimmer13k
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