Hello all! I'm trying to run a meta-analysis from different RNA-Seq datasets using the package metaRNASeq. I have run the differential expression analysis for the individual datasets using DESeq2 and I obtained the differential expressed genes and the p-values. DESeq2 gives a two-tailed p-value. My question is: should I transform the p-values from two-tailed to one-tailed or I can use them directly as two-tailed to perform the meta-analysis using metaRNASeq package? Thanks in advance!!
Question: p-values for metaRNASeq package
22 months ago by
mr.monahton • 20
mr.monahton • 20 wrote:
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