Retrieve the direction and reversibility of KEGG reactions

Question

[davidtmscott]

I have a few thousand metabolic reactions I got from KEGG that I would like to know the direction of and if they are reversible or not. I have found KEGG not to provide much accurate information on this as they seem to represent all reaction as reversible (<=>).

I am wondering is there any way to computationally extract this data accurately from KEGG or any other database?

Thanks

[AK]

Possible in MetaCyc. Have a look at: Determining Programmatically Whether Or Not A Reaction Is Reversible In Kegg (Or Metacyc).