Replicating ELAND alignment using Bowtie2

Question

[jacobcvt12]

I am attempting to replicate a workflow that used ELAND for alignment of reads. I don't have access to ELAND, but according to an article here,

Eland guarantees full sensitivity for hits with up to two mismatches

and ELAND

achieves full sensitivity given a threshold

is there a way to approximate this functionality in Bowtie2 by modifying some of the parameters? I see that there is a --very-sensitive argument, but I don't understand what level of sensitivity this targets, or for how many mismatches that sensitivity level is applicable.

[GenoMax]

ELAND has been deprecated for a decade. Any alignments you do with current aligners should be as good (or better) with default parameters. If you have the eland alignment available you can compare the stats on both.