Zn binding sites and active site location in conserved domain database (CDD)

Question

[Shicheng Guo]

Hi All,

I want to investigate the functional domains for gene ACE2. I am using the conserved domains database (CDD) to check the functional domains for gene ACE2. I notice there are 5 big domains for this protein including M2_ACE, M3_like and so on.

I noticed there are lots of Zn binding site and active site, I want to receive the positive just like “List of domain hits”, However, I didn’t see them. Is there any way to receive the position for these sites?

Thanks

Answer 1

[Mensur Dlakic]

Hovering over those triangles representing the active site will give you info about them. Clicking on them will open a separate page. If you want to automate the process, PfamScan has an option to look for active sites, and its search script is available here.