How to interpret SNP-based heritability estimate of 0 and 0.9999999?
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5.6 years ago

Hello, I have an SNP dataset of 717014 SNPs and a very small sample size (145). I have 50 traits that are quantitative. I have estimated the SNP-based heritability using the GCTA tool. And for most of the traits, I have got pretty good estimates with SE (0.1 to 0.2). But with the same sample size, I have got heritability estimates of "0" and 0.99999. Can you please explain why has that happened or how can I interpret it?

Thanks. Anik

snp genome • 873 views
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