Entering edit mode
4.2 years ago
iti.gupta
▴
10
Hello All, I need a help regarding connectivity map (or rather Lincs 1000) I queried my gene list (Up and Down) using clue.io and got a list of drugs from +100 to -100 connectivity score. Utilizing the data set provided in GEO (level 5) I fetched the z-score for my gene of interest for that particular drug. However, for a single drug i am getting multiple dosage and their respective z-score. I want to collapse these set of z-score into a single data point (as provided in the results from the query). Can someone please suggest which method to use? I tried checking their connectopedia help page and their paper as well but did not find anything. Also, I was planning of taking median. Will that be a correct approach?
