Has Anyone Tried Seqman Ngen?
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12.1 years ago
Dejian ★ 1.3k

SeqMan NGen is said to be able to assemble a genome on a desktop computer. It uses a patented algorithm. It provides a fully functional free trial. Has anyone tried it? Does it work that magically?

next-gen • 2.1k views
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12.1 years ago
ALchEmiXt ★ 1.9k

In my humble opinion; there is no such thing as a magic box with default settings in de novo assembly.

We tried the Ngen as well as one of its direct compettitors CLCbio genomic workbench...which also works from a desktop computer for smaller sized genomes....you still need quite some computational power if you want to do large eukaryotic stuff..... Currently for Illumina data 150bp+ we are quite comfortable with multiple kmer assemblies using ABYSS.

My 2ct.

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