Calculating in SEURAT, list of highly dysregulated genes across conditions in a particular cluster.
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11 months ago
singcell • 0

I am trying to integrate two datasets from different conditions using Seurat vignette "Integrating stimulated vs. control PBMC datasets" #3.1 I wanted to Identify highly dys-regulated genes or highlighting genes that exhibit dramatic responses across conditions in a particular cluster.

For example, in the scatter plots below dots further away from line are dysregulated (exhibit dramatic responses) but I need to supply the list of genes to label those outlier point (

My question is, Is there any way to label those outlier DOTS without knowing identity of those dots beforehand or to determine the list of genes belonging to a cluster that are exhibiting dramatic responses between two treatment conditions.

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rna-seq seurat Stimulated vs Control PBMCs • 314 views

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