Transcription regulation and CHIP-seq questions
0
0
Entering edit mode
4.0 years ago
jbrody11 • 0

Disclaimer: These questions are strictly for practice, not for submission as exam answers. I have tried to get help with these questions from my college instructor but he hasn't replied to me for two weeks ago now.

I am kindly asking for guidance in answering the following questions. I have included my answer attempts and thoughts below the three questions. Any help would be greatly appreciated. enter image description here

Answer: PWMx has a higher information content as it has 6 binding sites, while PWMy only has 4 binding sites. Therefore there will be more information content gathered from PWMx. Minus values in the PWMs would have a very small information content while large plus values would have a high information content thus if you have lots of low (minus) values and lots of high (plus) values, you will yield a higher information content.

enter image description here

enter image description here

Scores were calculated by adding the PWMx values that correspond to sequences a & b

ChIP-Seq sequencing sequence • 491 views
ADD COMMENT

Login before adding your answer.

Traffic: 1634 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6