How to find out p-value format in chip-seq .bed files from GEO
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3.8 years ago
geenkgo • 0

Hi,

I'm downloading chip-seq peak bed files from GEO and my goal is to combine replicates to a consensus bed file, using MPSC. For example: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM1207899

The question is, how do i find out if the p-value in the peak bed-file is -log10(p-value) , -10log10(p-value) or -100log10(p-value) ? There is no header row.

Thanks for your help !

ChIP-Seq geo pvalue • 1.3k views
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since there are also values between 1000 and 4000 in it, i would have guessed it's -10log10 or -100log10, but it's a pity that there is no other way to say for sure.

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3.8 years ago
igor 13k

It says that BED file was generated with MACS. According to the documentation:

The 5th column in this file is the -10*log10pvalue of peak region

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