Closed:Horvath's Epigenetic Clock and Coefficients

Question

[_program]

Hello,

I am trying to implement and better understand the Horvath's epigenetic clock.

By now, so far, I have computed the beta values with my noob programming skills. To accomplish that I just used the minfi package available on the bioconductor.

Now, I have two problems, the first one is to understand what I have to do next;

the second problem regards to the fact that I can easily compute (without understanding) the Horvath clock by implementing the wateRmelon package using the agep function, however, I would like to determine the Horvath Coefficients on my own.