Find SNVs that creates GT or AG Splicing

Question

[myname2020]

I have a list of variants and their positions. How can I determine whether it creates a GT or AG change that will cause abnormal splicing?

Answer 1

[colindaven]

Try using snpEff http://snpeff.sourceforge.net/ or Ensembl VEP https://www.ensembl.org/info/docs/tools/vep/index.html

If you have a list, that's not so good. You'll likely need VCF format. Also, check you get the genomic build (coordinates) correct.