Read counts from DCC or CIRI2 for differential expression with DESeq2?
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2.0 years ago

I am starting differential expression of circRNAs. I have used DCC and CIRI2 and have selected circRNAs detected by both methods.

Do I use read counts from DCC or CIRI2 for differential expression in DESeq2?

I don't think the average of read counts from DCC or CIRI2 is correct as they are different tools. The papers I have read are not that clear with what they do.

rna-seq circRNA differential expression dcc circ2 • 579 views
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