Detection of excess IBD segments in patients
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16 months ago
Apprentice ▴ 90

Hi.

I have SNP array data for 10 case and 100 control subjects. I think that the case subjects have local shared IBD segments on chromosome 10.

So, I would like to detect excess IBD segments in case subjects. I could identify shared IBD segments in each pair of the all subjects using SHAPEIT2 and GERMLINE software. However, I don't know how to identify where the excess IBD segments are in case subjects.

Could you tell me how I do should?

IBD sgements SNP • 361 views
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