Looking for a fast way to visualize the same region of many Hi-C datasets together
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9 months ago
changxu.fan ▴ 50

Dear community,

I'm interested in the 3D structure of one genomic region (take the MYC locus as an example), and I hope to visually examine this region across as many .hic files as I can collect. It seems laborious and error-prone to open each file on juicebox and navigate to that region (also need to reload gene annotation each time). I was wondering if there is a way, preferably a programmable way, to visualize this one region from multiple Hi-C datasets together, similar to visualizing multiple ATAC-seq tracks on a genome browser. It would also be great if there is a package to plot Hi-C contact map efficiently (preferably together with gene annotation), so that I can write a loop and plot all the files.

Thank you!

Hi-C juicer juicebox • 208 views
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