Identity-By-Descent Calculation In Wgs Data
1
2
Entering edit mode
8.8 years ago

What are the approaches folks are using for IBD calculation in whole genome data from extended families (4-generations)? Has anyone tried using the typical linkage-like software like merlin or genehunter?

sequencing • 2.2k views
ADD COMMENT
0
Entering edit mode

Thanks, Zev, for the answer below. This is a good resource, but solves a slightly different problem than what I had in mind. We have the pedigree structure and the genotype data and want to infer the IBD states of all individuals in the pedigree (so that we can perform non-parametric linkage analysis, basically).

ADD REPLY
2
Entering edit mode
ADD COMMENT

Login before adding your answer.

Traffic: 1897 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6