could I conduct colocalization analysis based on the GWAS results from Asia and eQTL from GTEx

Question

[961998723]

I am just dip my feet into the GWAS field. I got the GWAS summary data in Chinese population. I do not have the expression data on the same population. so I wanna conduct the colocalization analysis using eQTL from GTEx. As I known, GTEx(v8) includes up to 17% of individuals with non-European or admixed ancestry, including 103 African American and 12 Asian American individuals who have both whole genome sequencing and gene expression data. Could I perform the colocalization analysis using the GWAS summary data in Chinese population and all eQTL from GTEx?

[Helix]

Sorry for activating old thread. I had also a dilemma to use coloc or enloc (colocalization methods) in Asian population. Did you perform colocalization analysis with eQTL data from GTEx using Chinese GWAS summary statistics? Please let me know about your experiences.