Entering edit mode
3.2 years ago
dpc
▴
240
Hi, I am doing differential abundance analysis and finding out biomarker from gut metagenomic sequences. For biomarker analysis, I am using the LefSe tool which has a default LDA score of 2.00. Can I lower this cut-off and still can consider significantly different taxa as a biomarker? If yes, which minimum value I can take?
Thanks