Deleted:Can I calculate the effect size from log2FoldChange in gene expression?
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3.2 years ago
ev97 ▴ 20

Hello, I am new here. I am trying to solve my problem and I do not know if someone has asked this before. I searched about it, but I couldn't find something similar. If it is the case, I am sorry if I am asking you the same thing.

Just in case, can someone help me?

I have used DEseq2 tool for estimate gene expression and I want to rank the significant genes using another method to estimate the effect size. In order to estimate this effect, I want to calculate Hedge's g and Cohen's d. I know that there is a package named "effsize" which has both type of effect sizes.

https://www.rdocumentation.org/packages/effsize/versions/0.8.1/topics/cohen.d

However, I don't know how to use that function (cohen.d) with the DEseq2 results.

Do you know if it is possible to use log2foldchange values (from my DEseq2 results?

Thanks very much in advance

Regards

rna-seq RNA-Seq DESeq2 effect size effsize • 499 views
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