Question: Motif Enrichment In Intersection Between Several Genetic Elements
2
gravatar for Simar
6.4 years ago by
Simar20
Simar20 wrote:

I have noticed enrichment of specific sequence motif in intersection between two genetic elements.
I would like to know what enrichment analysis should I do (have checked previous posts, but haven't found anything about enrichment in intersection).

Example:
Genetic element A (for exmp. specific chromatin modification);
Genetic element B (for exmp. specific gene family promoter);
I have checked enrichment for motif in genetic elements A & B seperately- only slight fold enrichment compared to genomic background.
But when I look for motif in genetic elements A & B intersection - fold enrichment increases significantly.

What kind of correlation or other statistical test I should use here? How should I pick genomic background now?

enrichment motif • 1.5k views
ADD COMMENTlink modified 6.4 years ago • written 6.4 years ago by Simar20
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