Predicting Biologically Significant Snps
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11.3 years ago
Pappu ★ 2.1k

I am trying to figure out which SNP might change the structure and function of the translated protein based on the minor allele freq (MAF) >0.1 from 1000 genomes data and ensembl SIFT and Polychen scores. I am wondering if there are any other way of achieving the goal.

snp ensembl 1000genomes • 2.7k views
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Entering edit mode
11.3 years ago
Erik Garrison ★ 2.4k

Check out the variant effect predictor. You can use it to get annotations from a number of functional effect prediction systems, such as Gerp and Consed.

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11.3 years ago

The VAAST pipeline has a variant annotation tool (VAT). In addition the output can be used the GWAS tool VAAST.

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