Mapping Snps Into Genes Using Linkage Information
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10.5 years ago
dolores ▴ 20

Hi! I would like to ask a probably naïve question.

I have a list of SNPs and I'm giving them a score based on their relation with a set of known genes. For instance, a user selects a list of genes of interest, and all the SNPs related to these genes get a high score.

I already have a simple mapping SNP-gene and it gives scores whether the gene is in the promoter region, in a exonic or intronic region and so on. But I would like to know if I can use haplotypic information.

Is it possible to get the haplotype where every SNP is located so that I can give a score to all the genes in the haplotype? If so, I would have an extra source of scoring.

Does this make sense to you?

Thanks a lot!

snps mapping haplotype • 1.7k views
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