Forum:CADD Error in EXOMISER
0
0
Entering edit mode
3.0 years ago
shwetan • 0

I have downloaded the gnomad.genomes.r3.0.indel.tsv and gnomad.genomes.r3.0.indel.tsv.gz.tbi in my examiner folder and I gave the path in applications.properties as examiner-cli-12.1.0/data/2102_hg38/gnomad.genomes.r3.0.indel.tsv and both files are present in that data folder and I have made changes in iml file also but still I am getting the below error.

Exception encountered during context initialization - cancelling refresh attempt: org.springframework.beans.factory.UnsatisfiedDependencyException: Error creating bean with name 'exomiserCommandLineRunner': Unsatisfied dependency expressed through field 'analysisParser'; nested exception is org.springframework.beans.factory.UnsatisfiedDependencyException: Error creating bean with name 'analysisParser' defined in URL [jar:file:/Users/admin/Desktop/exomiser-cli-12.1.0/lib/exomiser-core-12.1.0.jar!/org/monarchinitiative/exomiser/core/analysis/AnalysisParser.class]: Unsatisfied dependency expressed through constructor parameter 0; nested exception is org.springframework.beans.factory.UnsatisfiedDependencyException: Error creating bean with name 'genomeAnalysisServiceProvider' defined in class path resource [org/monarchinitiative/exomiser/autoconfigure/genome/GenomeAnalysisServiceAutoConfiguration.class]: Unsatisfied dependency expressed through method 'genomeAnalysisServiceProvider' parameter 0; nested exception is org.springframework.beans.factory.BeanCreationException: Error creating bean with name 'org.monarchinitiative.exomiser.autoconfigure.genome.Hg38GenomeAnalysisServiceAutoConfiguration': Bean instantiation via constructor failed; nested exception is org.springframework.beans.BeanInstantiationException: Failed to instantiate [org.monarchinitiative.exomiser.autoconfigure.genome.Hg38GenomeAnalysisServiceAutoConfiguration$$EnhancerBySpringCGLIB$$408163f2]: Constructor threw exception; nested exception is org.monarchinitiative.exomiser.autoconfigure.ExomiserAutoConfigurationException: Failed to load/find file /Users/admin/Desktop/exomiser-cli-12.1.0/data/2102_hg38/exomiser-cli-12.1.0/data/2102_hg38/gnomad.genomes.r3.0.indel.tsv. Please check exomiser properties file points to a valid tabix .gz file. 2021-04-23 16:06:33.460 INFO 1628 --- [ main] ConditionEvaluationReportLoggingListener :

Error starting ApplicationContext. To display the conditions report re-run your application with 'debug' enabled. 2021-04-23 16:06:33.463 ERROR 1628 --- [ main] o.s.boot.SpringApplication : Application run failed

Help would be appreciated Thank you in advance

exomiser cadd • 722 views
ADD COMMENT

Login before adding your answer.

Traffic: 1990 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6